D41.1 Selection criteria to select in vitro bioassays for implementation and use

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D41.1 Selection criteria to select bioassays for implementation and use

Following intensive discussions we have established a number of selection criteria to determine whether a bioassay is applicable for the assessment of the chemical water quality. A range of projects have already focused on the - largely overlapping – assay characteristics and selection criteria for bioassays to be used in environmental monitoring (Leusch et al. 2012; OECD 2012; Agency et al. 2012).

D41.2 Establishment of trigger values and validation of bioassay panel

Surface water, groundwater, the sea or other brackish sources of drinking water production are generally exposed to a complex mixture of pollutants associated with household, industrial, and agricultural waste. Current environmental monitoring of these water bodies is based on a comparison between concentrations of chemically target analyzed priority pollutants (n=33+8) and their environmental threshold values.

Trigger values for investigation of hormonal activity in drinking water and its sources using CALUX bioassays

In May 2013, interim results were published in Environment International by scientists from BioDetection Systems B.V., the National Institute for Public Health and the Environment (RIVM) and the DEMEAU partner KWR Watercycle Research Institute.

Implementation of novel rapid and quantitative biassays for water quality monitoring

Poster for the DEMEAU project by DEMEAU colleagues Merijn Schriks, Sander van der Linden, Armelle Hebert, Ron van der Oost, Frederic Leusch, Cornelia Kienle, Bart van der Burg.

WP4.1 Selection and validation of bioassays for water quality assessment

The objectives of this work package are:

To select and validate a minimal panel of bioassays for cost-effective and comprehensive toxicity screening of water and waste water samples and compliance with current and future legislations

The following tasks (with deliverables and milestones) are planned:

T4.1.1: Selection criteria

Selection criteria for the bioassays, which will include a preliminary evaluation of performance characteristics, practical applicability, relevance and cost effectiveness, will be determined.